I've tried these things before. Use with caution, and definitely not on a work device. They never fully uninstall and you might be left with incorrect registry keys and other weirdness. May break updates as well.
I've had good success with Total Uninstall for this problem (with software in general). It does a diff of your registry and filesystem before/after installing an app, and after uninstall highlights lingering remnants. Over time you and it "learn" to filter out background changes unrelated to the install process.
No, Windhawk's rule for all mods is that they do not permanent changes, including to the registry. Disabling the mod and rebooting will erase all effects.
I don't need one. Look into how this stuff works. It's a pile of scripts and registry edits. It's very sloppy. Windows isn't Linux. The OS does not expect the user to do stuff like this and it's not built for it. This is how you get the "windows sucks it's always weird and broken" type people. Sure, you can do it, but you WILL have goofy unexplained problems if you mod your system with this stuff. If you want windows to be stable, stop fucking with it.