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So instead of natural selection making it so that people who live longer aren't affected by these issues - you'll have a populace that is dependent on a drug. Perfect recipe for powerful centralized control I suppose.


The drug is a shim until gene therapy is proven safe and effective. We are patching a bug in the human wrt the peptide hormone mechanism in scope. It is, very broadly speaking, a reward center defect. Morally speaking, we should show the human grace and attempt to assist humans with this buggy reward center at scale via bioengineering.

https://www.fractyl.com/fractyl-health-demonstrates-signific...


Declaring broad swaths of people "defective" because they don't subscribe to the same value is you seems quite dystopian to me. You say messiah, I say Nazi.


Having a medical condition isn't a moral failing; observing said medical conditions and advocating for providing help with potentially malfunctioning reward centers leading to lower agency and desired individual outcome doesn't strike me as "being a Nazi.". If a human doesn't want the help, they don't have to take it. If they do, make it widely and affordably available. Strange take. Context below.

https://recursiveadaptation.com/p/the-growing-scientific-cas...

> The consistency that I'm hearing from all across patient groups is gain of control, whereas previously, there was a loss of control… All of a sudden they're able to step back and say, 'oh, well I had this shopping phenomenon that was going on, gambling, addiction, or alcoholism, and all of a sudden, it just stopped,' -- Dr. Gitanjali Srivastava, Vanderbilt Medical Center

https://news.ycombinator.com/item?id=40357197 (comment from u/comova)

> 1. GLP-1 drugs appear to dramatically reduce addictive drive across substances. 2. GLP-1 drugs can reach vastly more patients than existing medications and they have positive mental health benefits for anxiety and depression. 3. This is our first ever opportunity to make a big dent in the addiction crisis, which kills 770,000 people a year between opioids, cigarettes, and alcohol.


So just like all the life saving drugs being prescribed now?


Or the vitamins that we fortify our bread and milk with.


Or the iodide we added to salt.

Prior to Iodized salt, Switzerland was suffering from a rash of people with Goiter, which is disfiguring and decreases your quality of life, and also a large population with cretinism which causes stunted growth and mental retardation.

Then, they introduced iodized salt, and those issues which used to be somewhat prevalent only 100 years ago are practically nonexistent now.

https://swissfederalism.ch/en/100-years-salt-iodination-swit...


Or thiamine added to white rice.

The hard way of finding out how bad polished white rice is for you - https://www.atlasobscura.com/articles/rice-disease-mystery-e...


We have destroyed natural selection in humans a long time ago when by creating effective healthcare, so don't worry about it.

There are many companies making different versions of this drug, I don't see why you think its some kind of conspiracy intended to control the masses, literally if the benefit is greater than the costs what is your issue with it?


The "benefit greater than the cost" is very much unproven. It's a psychoactive drug first and foremost, and one that deeply affects the reward mechanisms. What the sibling post calls "defects" I call variety, uniqueness, and not being a robot.




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