> Considering the potential neuroinvasion of SARS-CoV-2, antiviral therapy
should be carried out as early as possible to block its entry into the CNS. Airway inhalation of antiviral agents will be the first choice at the early stage of infection,
which will inhibit the replication SARS-CoV-2 in the respiratory tracts and lung and
prevent from its subsequent neuroinvasion. It is also urgent to find effective antiviral
drugs that can cross the blood-brain barrier. Moreover, corticosteroids, which are used
frequently for severe patients, may have no treatment effect, but rather accelerate the
replication of the virus within the neurons.
Yes, but it suggests that it could be important to distinguish whether the cause of their decline and hypoxia is CNS respiratory depression or issues with lung function before making that call.
